Common Bacterial Pathogen	Antimicrobial Therapy
16 – 50 yo	N meningitis, S pneumonia, H influ (nonimmunized pts)	Vanc plus 3rd gen ceph
> 50 yo	S pneumonia, N meningitis, L monocytogenes, aerobic gram-negative bacilli	Vanc plus 3rd gen ceph and ampicillin
Immunocompromised	L monocytogenes, aerobic gram-negative bacilli, S pneumonia, N meningitis	Vanc plus 3rd gen ceph and ampicillin
Neurosurgery, head trauma, cerebrospinal trauma	Staphylococci, aerobic gram-negative bacilli, S pneumonia	Vanc plus either 3rd gen ceph with anti-pseudomonal coverage or meropenem
From Emergency Medicine Practice september 2009, Vol 11, No 9

 

Antibiotic

Dose	Max dose	Interval
Ceftriaxone	50 mg/kg	2 gm	q 12 h
Vancomycin	15 mg/kg	500 mg	q 6 h
Ampicillin	50 mg/kg	3 gm	q 6 h
Cefepime	50 mg/kg	2 gm	q 8 h
Ceftazidime	50 mg/kg	2 gm	q 8 h
Cefotaxime	200 mg/kg/day
Meropenem	40 mg/kg	2 gm	q 8 h
Dexamethasone		10 mg	q 6 h